A-71915 (TFA) is a selective inhibitor of ANP receptor (atrial natriuretic peptide-receptor), induces apoptosis and decreases insulin secretion in RINm5F pancreatic β-cells.

Product information

Molecular Weight: 1727.98

Formula: C71H117F3N26O17S2

Chemical Name: 2, 2, 2-trifluoroacetic acid--2-((6R, 7R, 11R, 14S, 23R, 26S, 29S, 32S, 35S, 43aR)-11-((S)-2-amino-5-((diaminomethylene)amino)pentanamido)-26, 35-di((S)-sec-butyl)-6-carbamoyl-14-(cyclohexylmethyl)-7, 23, 32-tris(3-((diaminomethylene)amino)propyl)-1, 4, 12, 15, 18, 21, 24, 27, 30, 33, 36-undecaoxo-1, 2, 3, 4, 5, 6, 7, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 38, 43, 43a-hexatriacontahydro-10H-[1, 2]dithia[5, 8, 11, 14, 17, 20, 23, 26, 29, 32, 35]undecaazacyclooctatriacontino[11, 10-b]isoquinolin-29-yl)acetic acid (1/1)

Smiles: C[C@@H](CC)[C@@H]1NC(=O)[C@@H](CCCN=C(N)N)NC(=O)CNC(=O)CNC(=O)[C@H](CC2CCCCC2)NC(=O)[C@H](CSS[C@H](CCCN=C(N)N)[C@H](NC(=O)CNC(=O)[C@H]2CC3=CC=CC=C3CN2C(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(O)=O)NC1=O)[C@@H](C)CC)C(N)=O)NC(=O)[C@@H](N)CCCN=C(N)N.OC(=O)C(F)(F)F

InChiKey: UPTRWMPQMHVUKL-KUBBKVDSSA-N

InChi: InChI=1S/C69H116N26O15S2.C2HF3O2/c1-5-36(3)53-64(109)90-45(30-52(99)100)61(106)88-43(22-14-26-82-68(76)77)60(105)94-54(37(4)6-2)65(110)95-34-40-19-11-10-18-39(40)29-47(95)63(108)86-33-51(98)92-55(56(71)101)48(23-15-27-83-69(78)79)112-111-35-46(91-57(102)41(70)20-12-24-80-66(72)73)62(107)89-44(28-38-16-8-7-9-17-38)58(103)85-31-49(96)84-32-50(97)87-42(59(104)93-53)21-13-25-81-67(74)75;3-2(4,5)1(6)7/h10-11,18-19,36-38,41-48,53-55H,5-9,12-17,20-35,70H2,1-4H3,(H2,71,101)(H,84,96)(H,85,103)(H,86,108)(H,87,97)(H,88,106)(H,89,107)(H,90,109)(H,91,102)(H,92,98)(H,93,104)(H,94,105)(H,99,100)(H4,72,73,80)(H4,74,75,81)(H4,76,77,82)(H4,78,79,83);(H,6,7)/t36-,37-,41-,42+,43-,44-,45-,46-,47+,48+,53-,54-,55-;/m0./s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.