ZINC20451377 is a small molecule that binds to hepatitis B surface antigen (HBsAg) with high affinity (Kd=65.3 nM), reduces HBsAg levels and HBV virion secretion in cell culture model for HBV.

Product information

CAS Number: 2306303-35-3

Molecular Weight: 526.67

Formula: C32H38N4O3

Chemical Name: (E)-3-(4-methoxyphenyl)-1-(4-(3-((4-(pyridin-3-ylmethyl)piperazin-1-yl)methyl)phenoxy)piperidin-1-yl)prop-2-en-1-one(E)-3-(4-methoxyphenyl)-1-(4-(3-((4-(pyridin-3-ylmethyl)piperazin-1-yl)methyl)phenoxy)piperidin-1-yl)prop-2-en-1-one

Smiles: COC1C=CC(/C=C/C(=O)N2CCC(CC2)OC2C=C(CN3CCN(CC4=CN=CC=C4)CC3)C=CC=2)=CC=1

InChiKey: ACJMCFJDYXAPSD-FMIVXFBMSA-N

InChi: InChI=1S/C32H38N4O3/c1-38-29-10-7-26(8-11-29)9-12-32(37)36-16-13-30(14-17-36)39-31-6-2-4-27(22-31)24-34-18-20-35(21-19-34)25-28-5-3-15-33-23-28/h2-12,15,22-23,30H,13-14,16-21,24-25H2,1H3/b12-9+

Technical Data

Appearance: To be determined

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO, not in water

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.