Elab Fluor® Violet 450 Anti-Mouse CD161/NK1.1 Antibody [PK136]

Size: 100μg

Catalogue Number: E-AB-F0987UQ-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD161/NK1.1

Target Synonym: Killer cell lectin-like receptor subfamily B member 1C, Klrb1c, CD161 antigen-like family member C, Ly-55c, CD161/NK1.1, NKR-P1.9, NKR-P1C, NKR-P1 40, CD161c,

Conjugation: Elab Fluor® Violet 450

Host: Mouse

Species Reactivity: Mouse

Application: FCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Isotype: Mouse IgG2a, κ

Clone No.: PK136

UNIProt ID: P27814, P27812, Q99JB4,

Background: NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

Concentration: 0.5 mg/mL

Control Catalogue Number: E-AB-F09803Q

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

GeneID: 17059

Storage: This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.

Shipping: Ice bag