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Interchim puriFlash® 430 Flash Chromatography SystemThis is a rare opportunity to pick up a high end Interchim puriFlash 430 chromatography system at a fraction of the cost of a fully serviced unit. Known for fast, reliable prep flash separations, automated gradient control, and intuitive software, the 430 remains a workhorse in purification labs and contract facilities. The platform is ideal for organic synthesis, fraction collection, and method development and systems of this level are getting harder
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This is a rare opportunity to pick up a high-end Interchim puriFlash 430 chromatography system at a fraction of the cost of a fully serviced unit. Known for fast, reliable prep/flash separations, automated gradient control, and intuitive software, the 430 remains a workhorse in purification labs and contract facilities. The platform is ideal for organic synthesis, fraction collection, and method development — and systems of this level are getting harder to find on the secondary market.

This listing is for an Interchim puriFlash 430 instrument. The unit powers on and responds to controls, but it will require service before routine use — most notably replacement of the solvent inlet/solvent filters (likely interchangeable with Shimadzu style) and a basic service/flush.

Once serviced, it’s a strong value for a lab, service provider, or reseller who can handle final calibration and consumables, turning it into a dependable and profitable system.

Key technical notes & capabilities (from Interchim literature):

  • Designed for preparative flash purification (supports a wide range of flash columns and prep-LC columns). Column sizes and sample loading guidelines are listed in Interchim’s column guide (useful to size your intended workload). Mz-at

  • Typical operating ranges for the puriFlash family: flow ranges and max pressures that support flash/prep formats (see Interchim column specifications for exact max flows per cartridge size). Example column specs and loading charts are in Interchim’s brochure. Mz-at

What I’m including with the sale:

  • puriFlash 430 main unit (instrument chassis & control panel)

  • Multiple fraction collector racks (for different vial/tube volumes — see photos)

  • External column stand / column holder for larger cartridges/columns

  • Power cord

Known issues / condition (important):

  • Unit powers on and display/controls respond (basic power/boot confirmed).

  • Requires replacement solvent filters (we recommend replacing inlet filters and thoroughly flushing solvent lines prior to use). This is the primary maintenance item known at time of listing.

  • Cosmetic wear consistent with normal lab use (scratches / scuffs). Please review photos carefully.

Why buy this unit?

  • Good candidate for refurbishment or as a parts donor — Interchim offers spare parts and service parts for puriFlash models (parts like pump piston kits, valves, column holder adapters, back-pressure regulators, etc. are available). See the Interchim spare-parts catalog for PF430 items and part numbers. Interchim+1


Maintenance checklist (recommended before first run)

(These are recommended steps — local service or a qualified technician is advised.)

  1. Replace solvent inlet / inline filters and inspect filter housings. (Known to be needed for this unit.)

  2. Flush all solvent lines and degas; run pump priming procedures.

  3. Replace or inspect pump seals / piston kit (common wear items — P/Ns available from Interchim). Interchim

  4. Check/clean injector valves and any sample loop or dry-load hardware.

  5. Verify detector lamp (UV) and run a test gradient to confirm fraction collection triggering.

  6. Update / verify InterSoft® X software connection and method files (tutorials below). YouTube

(Parts and accessories for PF430 are listed on Interchim’s spare parts pages — many service parts are available for order.) Interchim


Helpful spare-part P/N examples

  • PFS070 — Pump module piston kit (common maintenance kit for pump service). Interchim

  • PFS220 — Pump module pull-piston (seal kit). Interchim

  • FO3980 — Example back-pressure regulator listing for PF215/PF430/PF450 (see Interchim spare parts pages). 

Interchim puriFlash® 430 Flash Chromatography System

Item no : 96341115199
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US$ 4724.49
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