It's 2032. The planet is now ruled by the World Coalition Government which annexed 80% of the countries, with the remaining quickly dragged into the WCG. While their official goal was to solve humankind's problems, it was about money. Massive spending bankrupted poorer countries, and soon all traces of individual government disappeared. For those who were poor, the situation didn't improved one bit, and for the richer, maintaining the status was done at the expense of their privacy and personal freedoms. To make things worse, life outside the major cities, far from the atmosphere processors is nearly impossible, as the so-called "Wilderness Preserves" are poisoned, and those who venture into them risk a painful death.

Konoko, fresh out from TCTF (Technology Crimes Task Force, a secret police to take cyber drugs and weapons from the streets, as well as explore the induced technophobia to operate and investigate on a blank check permission) academy is placed under the command of Terrance Griffin and Dr. Kerr and linked to a SLD - an android - called Shinatama, who is neurally linked to her. However, Konoko knows next to nothing about her past, other that she was orphaned at the age of three and felt "different" to other people while was being brought up under the wing of TCTF. After many years in training, she has finally the chance to prove herself to Griffin and the TCTF, and so, heads for a warehouse rumoured to be under the control of the Syndicate, a criminal organization which grew exponentially after a young man called "Boss Muro" climbed to the top of the organization.

Inspired by the classic Anime series Ghost in the Shell by Shirow Masamune, gameplay is a mix between generic third-person shooter and a classic beat'em up. While Konoko has at her disposal several hand-to-hand acrobatic moves (with more unlocked as the player advances), she can also find weapons in the levels, and the decision to go armed or bare-fisted is only up to the player. Each weapon either draws from ballistic or energy cell clips, the number of rounds in each clip depending on the weapon: a Black Adder (a short, one-hand machine gun like an Uzi) can get 30 rounds from a ballistic clip, while a Mercury Bow (a sniper railgun sans scope) only two. Combined with the limited availability of clips, this adds a strategic element to the game, as the player can only carry a weapon at a time, so if a powerful weapons runs out of ammo, the player must choose between keeping the weapon and fight hand to hand with the enemies until Konoko finds fresh ammo clips, or discard it for a lesser gun that uses different ammo. However, if the player runs out of ammo completely when facing a tough challenge, Konoko can "overdose" on hypo sprays (used to heal damage) by using them over her natural health bar, which provides her with faster movement and tougher blows.