• Helps Enhance Mood And Neural Function
• Helps Promote Joint Comfort And Mobility
• Helps Support Liver Health And Detoxification
• Dietary Supplement
• Vegan
• Gluten Free
• Soy Free

SAM-e (S-Adenosyl Methionine) is naturally produced by your body and helps maintain healthy emotions. Various factors such as diet and aging can cause low levels of SAM-e, leaving you feeling unbalanced and moody. Doctor's Best SAM-e helps replenish your SAM-e levels and promote a healthy mood.

Supplementing with SAM-e

Soloesse’ Italian SAM-e is processed to yield the highest available percentage of the active pure S.S form which helps mediate biochemical activity in the human body.

SAM-e and Mood and Cognitive Function

SAM-e helps facilitate DNA enzymatic actions.These enzymatic actions are required for the healthy conversion of neurotransmitters responsible for healthy emotions, such as serotonin and dopamine. SAM-e also facilitates glutathione usage which improves the body's antioxidant defense and helps maintain acetylcholine levels necessary for cognitive function.

SAM-e and Joint Function

In clinical trials, SAM-e has been shown to help increase joint comfort and mobility by promoting the synthesis of proteoglycans, essential components of connective tissue.

SAM-e and Liver Function

SAM-e helps support healthy levels of glutathione, a critical antioxidant which helps protect against free radicals. SAM-e acts as a methyl donor in the synthesis and formation of phosphatidylcholine and L-cysteine, both necessary for maintaining liver health.

Our Double Strength SAM-e 400 contains 400mg of active Soloesse SAM-e in each tablet. Doctor's Best utilizes only the highest quality Italian Soloesse' SAM-e available providing slow and targeted release for improved Cl tolerance and absorption. This ensures that you receive the most potent SAM-e product with the highest percentage of the active S,S form per serving.